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英文名称： WDR77 Antigen (Recombinant Protein)
别 名： WD repeat domain 77; p44; MEP50; MEP-50; HKMT1069; Nbla10071; p44/Mep50
储 存： 冷冻（-20℃）
相关类别： 抗原
概述
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Fusion protein corresponding to a region derived from 132-331 amino acids of human WDR77 |
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Full name: |
WD repeat domain 77 |
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Synonyms: |
p44; MEP50; MEP-50; HKMT1069; Nbla10071; p44/Mep50 |
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Swissprot: |
Q9BQA1 |
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Gene Accession: |
BC009411 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
WDR77 is a component of the 20S PRMT5 (MIM 604045)-containing methyltransferase complex, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins (see MIM 601061). This modification targets Sm proteins to the survival of motor neurons (SMN) complex (see MIM 600354) for assembly into small nuclear ribonucleoprotein core particles (Friesen et al., 2002 [PubMed 11756452]). |
