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英文名称： ZBTB44 Antigen (Recombinant Protein)
别 名： zinc finger and BTB domain containing 44; BTBD15; ZNF851; HSPC063
相关类别： 抗原
储 存： 冷冻（-20℃）
概述
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Fusion protein corresponding to a region derived from 371-570 amino acids of human ZBTB44 |
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Full name: |
zinc finger and BTB domain containing 44 |
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Synonyms: |
BTBD15; ZNF851; HSPC063 |
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Swissprot: |
Q8NCP5 |
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Gene Accession: |
BC030580 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Zinc finger and BTB domain-containing protein 44 (ZBTB44), also known as BTBD15, is a 570 amino acid member of the Krüppel C2H2-type zinc-finger protein family. Localized to the nucleus, ZBTB44 contains a BTB domain, also known as a POZ domain, which inhibits DNA binding and mediates homotypic and heterotypic dimerization. Characteristics of the BTB domain suggest that ZBTB44 functions as a transcription regulator. Four isoforms of ZBTB44 have been identified. |
