手机扫码访问本站
微信咨询
英文名称： ZGPAT Antigen (Recombinant Protein)
别 名：zinc finger CCCH-type and G-patch domain containing; ZIP; ZC3H9; GPATC6; GPATCH6; ZC3HDC9; KIAA1847
储 存： 冷冻（-20℃）
相关类别： 抗原
概述
|
Fusion protein corresponding to a region derived from 332-531 amino acids of human ZGPAT |
|
Full name: |
zinc finger CCCH-type and G-patch domain containing |
|
Synonyms: |
ZIP; ZC3H9; GPATC6; GPATCH6; ZC3HDC9; KIAA1847 |
|
Swissprot: |
Q8N5A5 |
|
Gene Accession: |
BC019338 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
Transcription repressor that specifically binds the 5'-GGAG[GA]A[GA]A-3' consensus sequence. Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival and migration. Its ability to repress genes of the EGFR pathway suggest it may act as a tumor suppressor. Able to suppress breast carcinogenesis. |
