兔抗PRKG2多克隆抗体

Background:

cGKII (cGMP-dependent protein kinase type II) is a major receptor of intracellular cGMP and mediates a plethora of physiological responses. cGKII contains a conserved leucine zipper motif at the amino-terminus. It is expressed in small intestine, colon, prostate, and human brain tissues, and the cGKII gene maps to chromosome 4q13.1-q21.1. cGKII has been shown to regulate the ion transport system in the intestine. Myristoylation of the penultimate glycine in cGKII appears to be essential for directing cGKII to the membrane, since cGKII is devoid of any hydrophobic transmembrane domains. The translocation of cGKII from the cytosol to the membrane allows it to function properly in regulating intestinal ion transport.

Applications:

ELISA, WB, IHC

Name of antibody:

PRKG2

Immunogen:

Synthetic peptide of human PRKG2

Full name:

protein kinase, cGMP-dependent, type II

Synonyms：

cGKII; PRKGR2

SwissProt:

Q13237

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human liver cancer and Human cervical cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

87 kDa

WB Positive control:

Mouse brain and lung tissue

WB Recommended dilution:

200-1000