兔抗SCN1B多克隆抗体

Background:

Voltage-gated sodium channels are heteromeric proteins that function in the generation and propagation of action potentials in muscle and neuronal cells. They are composed of one alpha and two beta subunits, where the alpha subunit provides channel activity and the beta-1 subunit modulates the kinetics of channel inactivation. This gene encodes a sodium channel beta-1 subunit. Mutations in this gene result in generalized epilepsy with febrile seizures plus, Brugada syndrome 5, and defects in cardiac conduction.

Applications:

ELISA, IHC

Name of antibody:

SCN1B

Immunogen:

Synthetic peptide of human SCN1B

Full name:

sodium channel, voltage-gated, type I, beta subunit

Synonyms：

ATFB13; BRGDA5; GEFSP1

SwissProt:

Q07699

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human liver cancer and Human esophagus cancer

IHC Recommend dilution:

25-100