兔抗STARD4多克隆抗体

Background:

Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1; MIM 184756) and by liver X receptors (e.g., LXRA; MIM 602423). Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regulatory protein (STAR; MIM 600617). STAR is homologous to a family of proteins containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain, including STARD4 (Soccio et al., 2002 [PubMed 12011452]).

Applications:

ELISA, WB, IHC

Name of antibody:

STARD4

Immunogen:

Synthetic peptide of human STARD4

Full name:

StAR-related lipid transfer domain containing 4

SwissProt:

Q96DR4

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human tonsil

IHC Recommend dilution:

25-100

WB Predicted band size:

24 kDa

WB Positive control:

Human fetal liver tissue，Mouse liver tissue lysates

WB Recommended dilution:

200-1000