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技术规格
Background:
This gene encodes a member of the sestrin family of stress-induced proteins. The encoded protein reduces the levels of intracellular reactive oxygen species induced by activated Ras downstream of RAC-alpha serine/threonine-protein kinase (Akt) and FoxO transcription factor. The protein is required for normal regulation of blood glucose, insulin resistance and plays a role in lipid storage in obesity. Alternative splicing results in multiple transcript variants.
Applications:
ELISA, WB
Name of antibody:
SESN3
Immunogen:
Full length fusion protein
Full name:
sestrin 3
Synonyms:
SEST3
SwissProt:
P58005
ELISA Recommended dilution:
1000-2000
WB Predicted band size:
57 kDa
WB Positive control:
Mouse heart tissue
WB Recommended dilution:
200-1000