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技术规格
Background:
The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein.
Applications:
WB
Name of antibody:
SDC1
Immunogen:
Synthesized peptide derived from internal of human SDC1.
Full name:
syndecan 1
Synonyms:
SDC; CD138; SYND1; syndecan
SwissProt:
P18827
WB Predicted band size:
32 kDa
WB Positive control:
Hela cells lysate
WB Recommended dilution:
500-3000