兔抗SLC9A3R1多克隆抗体

Background:

This gene encodes a sodium/hydrogen exchanger regulatory cofactor. The protein interacts with and regulates various proteins including the cystic fibrosis transmembrane conductance regulator and G-protein coupled receptors such as the beta2-adrenergic receptor and the parathyroid hormone 1 receptor. The protein also interacts with proteins that function as linkers between integral membrane and cytoskeletal proteins. The protein localizes to actin-rich structures including membrane ruffles, microvilli, and filopodia. Mutations in this gene result in hypophosphatemic nephrolithiasis/osteoporosis type 2, and loss of heterozygosity of this gene is implicated in breast cancer.

Applications:

ELISA, IHC

Name of antibody:

SLC9A3R1

Immunogen:

Synthetic peptide of human SLC9A3R1

Full name:

SLC9A3 regulator 1

Synonyms:

EBP50; NHERF; NHERF1; NHERF-1; NPHLOP2

SwissProt:

O14745

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human liver cancer

IHC Recommend dilution:

20-100