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英文名称: Anti-SP1 (Phospho-Thr739) rabbit polyclonal antibody
相关类别: 一抗
储 存: 冷冻(-20℃) 避光
宿 主: Rabbit
抗 原: SP1 (Phospho-Thr739)
反应种属: Human Mouse Rat
标 记 物: Unconjugate
克隆类型: rabbit polyclonal
技术规格
Background:
Transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR-alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter. Plays an essential role in the regulation of FE65 gene expression.
Applications:
WB
Name of antibody:
SP1 (Phospho-Thr739)
Immunogen:
Synthetic peptide of human SP1 (Phospho-Thr739)
Full name:
Sp1 transcription factor (Phospho-Thr739)
SwissProt:
P08047
WB Predicted band size:
81 kDa
WB Positive control:
NIH/3T3 cells treated with serum starvation
WB Recommended dilution:
500-1000