兔抗TEK(Phospho-Tyr992)多克隆抗体

Background:

This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains, three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats. The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Mutations in this gene are associated with inherited venous malformations of the skin and mucous membranes.

Applications:

WB

Name of antibody:

TEK(Phospho-Tyr992)

Immunogen:

Peptide sequence around phosphorylation site of tyrosine 992 (E-V-Y(p)-V-K) derived from Human TIE2.

Full name:

TEK tyrosine kinase, endothelial

Synonyms：

TIE2; VMCM; TIE-2; VMCM1; CD202B

SwissProt:

Q02763

WB Predicted band size:

126 kDa

WB Positive control:

HepG2 cells lysates

WB Recommended dilution:

500-1000