兔抗RRAGA多克隆抗体

Background:

Ras-related GTP-binding protein A is a protein that in humans is encoded by the RRAGAgene. Guanine nucleotide-binding protein forming heterodimeric Rag complexes required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids. Involved in the RCC1/Ran-GTPase pathway. May play a direct role in a TNF-alpha signaling pathway leading to induction of cell death.

Applications:

ELISA, WB, IHC

Name of antibody:

RRAGA

Immunogen:

Fusion protein of human RRAGA

Full name:

Ras-related GTP binding A

Synonyms：

FIP1; RAGA; FIP-1

SwissProt:

Q7L523

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human breast cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

37 kDa

WB Positive control:

Hepg2 and hela cells

WB Recommended dilution:

500-2000