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技术规格
Background:
HACE1 (HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1), also known as KIAA1320, is a 909 amino acid protein that localizes to both the cytoplasm and the endoplasmic reticulum and contains one HECT domain and six ANK repeats. Expressed in kidney, heart and brain, HACE1 functions as an E3 ubiquitin-protein ligase that interacts with the proteasome and is thought to play a role in protein degradation. HACE1 is downregulated in Wilms tumor, suggesting a possible role in tumor suppression.
Applications:
ELISA, IHC
Name of antibody:
HACE1
Immunogen:
Synthetic peptide of human HACE1
Full name:
HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1
SwissProt:
Q8IYU2
ELISA Recommended dilution:
2000-5000
IHC positive control:
Human colon cancer and Human ovarian cancer
IHC Recommend dilution:
100-200