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Background:
This gene encodes an enzyme that plays a role in the recovery of retinal photoreceptors from photobleaching. This enzyme promotes the activity of retinal guanylyl cyclase-1 (GC1) at low calcium concentrations and inhibits GC1 at high calcium concentrations. Mutations in this gene can cause cone dystrophy 3 and code-rod dystrophy 14. Alternative splicing results in multiple transcript variants.
Applications:
ELISA, IHC
Name of antibody:
GUCA1A
Immunogen:
Fusion protein of human GUCA1A
Full name:
guanylate cyclase activator 1A
Synonyms:
COD3; GCAP; GUCA; GCAP1; GUCA1; CORD14; C6orf131
SwissProt:
P43080
ELISA Recommended dilution:
5000-10000
IHC positive control:
Human colorectal cancer and Human tonsil
IHC Recommend dilution:
100-300