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技术规格
Background:
The protein encoded by this gene is a small GTPase that acts as a homodimer. The encoded protein is activated by the guanine nucleotide exchange factor PREB and is involved in protein transport from the endoplasmic reticulum to the Golgi. This protein is part of the COPII coat complex. Defects in this gene are a cause of chylomicron retention disease (CMRD), also known as Anderson disease (ANDD). Two transcript variants encoding the same protein have been found for this gene.
Applications:
ELISA, IHC
Name of antibody:
SAR1B
Immunogen:
Fusion protein of human SAR1B
Full name:
secretion associated, Ras related GTPase 1B
Synonyms:
ANDD; CMRD; GTBPB; SARA2
SwissProt:
Q9Y6B6
ELISA Recommended dilution:
1000-2000
IHC positive control:
Human thyroid cancer and human liver cancer
IHC Recommend dilution:
25-100