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Background:
The epsilon globin gene (HBE) is normally expressed in the embryonic yolk sac: two epsilon chains together with two zeta chains (an alpha-like globin) constitute the embryonic hemoglobin Hb Gower I; two epsilon chains together with two alpha chains form the embryonic Hb Gower II. Both of these embryonic hemoglobins are normally supplanted by fetal, and later, adult hemoglobin. The five beta-like globin genes are found within a 45 kb cluster on chromosome 11 in the following order: 5'-epsilon - G-gamma - A-gamma - delta - beta-3'.
Applications:
ELISA, WB, IHC
Name of antibody:
HBE1
Immunogen:
Fusion protein of human HBE1
Full name:
hemoglobin subunit epsilon 1
Synonyms:
HBE
SwissProt:
P02100
ELISA Recommended dilution:
5000-10000
IHC positive control:
Human tonsil
IHC Recommend dilution:
30-150
WB Predicted band size:
16 kDa
WB Positive control:
Human placenta tissue lysate
WB Recommended dilution:
500-2000