兔抗PRKCA(Phospho-Tyr657)多克隆抗体

Background:

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members.

Applications:

WB

Name of antibody:

PRKCA(Phospho-Tyr657)

Immunogen:

Peptide sequence around phosphorylation site of tyrosine 657(F-S-Y(p)-V-N) derived from Human PKC α.

Full name:

protein kinase C, alpha

Synonyms:

AAG6; PKCA; PRKACA; PKC-alpha

SwissProt:

P17252

WB Predicted band size:

77 kDa

WB Positive control:

COLO205 lysates

WB Recommended dilution:

500-1000