兔抗SOCS1多克隆抗体

Background:

This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival.

Applications:

ELISA, WB, IHC

Name of antibody:

SOCS1

Immunogen:

Synthetic peptide of human SOCS1

Full name:

Suppressor of cytokine signaling 1

Synonyms：

JAB, CIS1, SSI1, TIP3, CISH1, SSI-1, SOCS-1

SwissProt:

O15524

ELISA Recommended dilution:

2000-10000

IHC positive control:

Human liver cancer and Human ovarian cancer

IHC Recommend dilution:

100-300

WB Predicted band size:

24 kDa

WB Positive control:

HT-29 and 231 cells

WB Recommended dilution:

500-2000