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技术规格
Background:
The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis.
Applications:
ELISA, IHC
Name of antibody:
SELE
Immunogen:
Fusion protein of human SELE
Full name:
selectin E
Synonyms:
ELAM; ESEL; CD62E; ELAM1; LECAM2
SwissProt:
P16581
ELISA Recommended dilution:
2000-5000
IHC positive control:
Human esophagus cancer and Human lung cancer
IHC Recommend dilution:
50-200