兔抗PTK6多克隆抗体

Background:

The protein encoded by this gene is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of this gene has been detected at low levels in some breast tumors but not in normal breast tissue. The encoded protein has been shown to undergo autophosphorylation. Alternative splicing results in multiple transcript variants.

Applications:

ELISA, IHC

Name of antibody:

PTK6

Immunogen:

Fusion protein of human PTK6

Full name:

protein tyrosine kinase 6

Synonyms:

BRK

SwissProt:

Q13882

IHC positive control:

Human gastric cancer

IHC Recommend dilution:

50-200