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Background:
This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. The encoded protein binds directly to retinoblastoma protein, which regulates cell proliferation. It interacts preferentially with the underphosphorylated retinoblastoma protein via the E1A-binding pocket B. Three alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.
Applications:
ELISA, WB
Name of antibody:
RBBP5
Immunogen:
Fusion protein of human RBBP5
Full name:
retinoblastoma binding protein 5
Synonyms:
RBQ3; SWD1
SwissProt:
Q15291
ELISA Recommended dilution:
1000-2000
WB Predicted band size:
59 kDa
WB Positive control:
Hela, hepg2 and HT-29 cells
WB Recommended dilution:
200-1000