兔抗RAB29多克隆抗体

Background:

The small GTPases Rab are key regulators in vesicle trafficking (PubMed:24788816). Essential for maintaining the integrity of the endosome-trans-Golgi network structure (By similarity). Together with LRRK2, plays a role in the retrograde trafficking pathway for recycling proteins, such as mannose 6 phosphate receptor (M6PR), between lysosomes and the Golgi apparatus in a retromer-dependent manner (PubMed:24788816). Recruits LRRK2 to the Golgi complex and stimulates LRRK2 kinase activity (PubMed:29212815). Regulates neuronal process morphology in the intact central nervous system (CNS) (By similarity). May play a role in the formation of typhoid toxin transport intermediates during Salmonella enterica serovar Typhi (S.Typhi) epithelial cell infection (PubMed:22042847).

Applications:

ELISA, IHC

Name of antibody:

RAB29

Immunogen:

Fusion protein of human RAB29

Full name:

RAB29, member RAS oncogene family

Synonyms:

RAB7L; RAB7L1

SwissProt:

O14966

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human prostate cancer and Human gastric cancer

IHC Recommend dilution:

100-300