兔抗SLC7A11多克隆抗体

Background:

This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death.

Applications:

ELISA, WB, IHC

Name of antibody:

SLC7A11

Immunogen:

Synthetic peptide of human SLC7A11

Full name:

solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11

Synonyms：

xCT; CCBR1

SwissProt:

Q9UPY5

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human brain and Human thyroid cancer

IHC Recommend dilution:

20-100

WB Predicted band size:

55 kDa

WB Positive control:

K562 and hepg2 cell

WB Recommended dilution:

500-2000