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技术规格
Background:
PTRH2 (peptidyl-tRNA hydrolase 2), also known as BIT1 (Bcl-2 inhibitor of transcription 1), is a 179 amino acid mitochondrial protein. During apoptosis, PTRH2 is released from the mitochondia to the cytoplasm. Once in the cytoplasm, PTRH2 regulates the function of two transcriptional regulators, TLE5 and TLE1, thereby promoting caspase-independent cell death. It is also believed that the natural substrate for PTRH2 may be petidyl-tRNAs, which leave the ribosomes during protein synthesis.
Applications:
ELISA, WB, IHC
Name of antibody:
PTRH2
Immunogen:
Fusion protein of human PTRH2
Full name:
peptidyl-tRNA hydrolase 2
Synonyms:
BIT1; PTH2; CFAP37; CGI-147
SwissProt:
Q9Y3E5
ELISA Recommended dilution:
2000-10000
IHC positive control:
Human breast cancer
IHC Recommend dilution:
10-50
WB Predicted band size:
19 kDa
WB Positive control:
Raji, Jurkat, 231, hepg2 and K562 cells
WB Recommended dilution:
1000-5000