兔抗PTPRC多克隆抗体

Background:

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling.

Applications:

ELISA, IHC

Name of antibody:

PTPRC

Immunogen:

Synthetic peptide of human PTPRC

Full name:

protein tyrosine phosphatase, receptor type, C

Synonyms：

LCA; LY5; B220; CD45; L-CA; T200; CD45R; GP180

SwissProt:

P08575

ELISA Recommended dilution:

1000-5000

IHC positive control:

Human Lymphoma and Human gastric cancer

IHC Recommend dilution:

50-200