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技术规格
Background:
This gene encodes an enzyme belonging to the short-chain dehydrogenases/reductases (SDR) family. This retinol dehydrogenase functions to catalyze the final step in the biosynthesis of 11-cis retinaldehyde, which is the universal chromophore of visual pigments. Mutations in this gene cause autosomal recessive fundus albipunctatus, a rare form of night blindness that is characterized by a delay in the regeneration of cone and rod photopigments. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream BLOC1S1 (biogenesis of lysosomal organelles complex-1, subunit 1) gene.
Applications:
ELISA, IHC
Name of antibody:
RDH5
Immunogen:
Fusion protein of human RDH5
Full name:
retinol dehydrogenase 5
Synonyms:
RDH1; 9cRDH; SDR9C5; HSD17B9
SwissProt:
Q92781
ELISA Recommended dilution:
5000-10000
IHC positive control:
Human brain
IHC Recommend dilution:
50-100