兔抗SETMAR多克隆抗体

Background:

This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants.

Applications:

ELISA, IHC

Name of antibody:

SETMAR

Immunogen:

Fusion protein of human SETMAR

Full name:

SET domain and mariner transposase fusion gene

Synonyms:

Mar1; METNASE

SwissProt:

Q53H47

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human esophagus cancer

IHC Recommend dilution:

50-300