兔抗RPS6KB2(Phospho-Ser423) 多克隆抗体

Background:

This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates the S6 ribosomal protein and eucaryotic translation initiation factor 4B (eIF4B). Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation.

Applications:

WB

Name of antibody:

RPS6KB2(Phospho-Ser423)

Immunogen:

Peptide sequence around phosphorylation site of Serine 423 (P-V-S(p)-P-L) derived from Human p70 S6 Kinase beta.

Full name:

ribosomal protein S6 kinase, 70kDa, polypeptide 2

Synonyms：

KLS; SRK; S6K2; STK14B; p70S6Kb; P70-beta; S6K-beta2; P70-beta-1; P70-beta-2; p70(S6K)-beta

SwissProt:

Q9UBS0

WB Predicted band size:

53 kDa

WB Positive control:

K562 cells lysates untreated or treated with EGF

WB Recommended dilution:

500-1000