兔抗POLG2多克隆抗体

Background:

This gene encodes the processivity subunit of the mitochondrial DNA polymerase gamma. The encoded protein forms a heterotrimer containing one catalytic subunit and two processivity subunits. This protein enhances DNA binding and promotes processive DNA synthesis. Mutations in this gene result in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions.

Applications:

IHC

Name of antibody:

POLG2

Immunogen:

Synthesized peptide derived from internal of human POLG2.

Full name:

polymerase (DNA directed), gamma 2, accessory subunit

Synonyms：

HP55; POLB; PEOA4; POLGB; MTPOLB; POLG-BETA

SwissProt:

Q9UHN1

IHC positive control:

Human cervix carcinoma tissue

IHC Recommend dilution:

50-100