兔抗RNF7多克隆抗体

Background:

The protein encoded by this gene is a highly conserved ring finger protein. It is an essential subunit of SKP1-cullin/CDC53-F box protein ubiquitin ligases, which are a part of the protein degradation machinery important for cell cycle progression and signal transduction. This protein interacts with, and is a substrate of, casein kinase II (CSNK2A1/CKII). The phosphorylation of this protein by CSNK2A1 has been shown to promote the degradation of IkappaBalpha (CHUK/IKK-alpha/IKBKA) and p27Kip1(CDKN1B).

Applications:

ELISA, IHC

Name of antibody:

RNF7

Immunogen:

Fusion protein of human RNF7

Full name:

ring finger protein 7

Synonyms：

SAG; ROC2; CKBBP1

SwissProt:

Q9UBF6

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human liver cancer and human tonsil

IHC Recommend dilution:

20-100