兔抗POLR2K多克隆抗体

Background:

PCID2 is expressed in immature and early-stage B lymphocytes and regulates expression of the mitotic checkpoint protein MAD2. Required for B-cell survival through the regulation of the expression of cell-cycle checkpoint MAD2L1 protein during B cell differentiation (By similarity). Component of the TREX-2 complex (transcription and export complex 2), composed of at least ENY2, GANP, PCID2, DSS1, and either centrin CETN2 or CETN3 (PubMed:22307388). The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket).

Applications:

ELISA, WB, IHC

Name of antibody:

PCID2

Immunogen:

Fusion protein of human PCID2

Full name:

PCI domain containing 2

Synonyms：

F10

SwissProt:

Q5JVF3

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human esophagus cancer and Human gastric cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

46 kDa

WB Positive control:

Human placenta tissue

WB Recommended dilution:

200-1000