兔抗TGFBR1多克隆抗体

Background:

The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene.

Applications:

ELISA, IHC

Name of antibody:

TGFBR1

Immunogen:

Synthetic peptide of human TGFBR1

Full name:

transforming growth factor, beta receptor 1

Synonyms:

AAT5; ALK5; MSSE; SKR4; ALK-5; LDS1A; LDS2A; TGFR-1; ACVRLK4

SwissProt:

P36897

IHC positive control:

Human gastric cancer

IHC Recommend dilution:

100-300