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英文 名称: Anti-TPM1 rabbit polyclonal antibody
别 名: CMH3; TMSA; CMD1Y; C15orf13; HTM-alpha
抗 原: TPM1
储 存: 冷冻(-20℃)
宿 主: Rabbit
相关类别: 一抗
反应种属: Human, Mouse, Rat
标 记 物: Unconjugate
克隆类型: rabbit polyclonal
技术规格
Background:
This gene is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The encoded protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction. In smooth muscle and non-muscle cells, alternatively spliced transcript variants encoding a range of isoforms have been described. Mutations in this gene are associated with type 3 familial hypertrophic cardiomyopathy.
Applications:
ELISA, WB, IHC
Name of antibody:
TPM1
Immunogen:
Fusion protein of human TPM1
Full name:
Tropomyosin 1 (alpha)
Synonyms:
CMH3; TMSA; CMD1Y; C15orf13; HTM-alpha
SwissProt:
P09493
ELISA Recommended dilution:
2000-5000
IHC positive control:
Human gastric cancer and human breast cancer
IHC Recommend dilution:
50-200
WB Predicted band size:
33 kDa
WB Positive control:
Mouse heart and muscle tissue
WB Recommended dilution:
500-2000