兔抗PTK2 (Phospho-Tyr861)多克隆抗体

Background:

Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Plays a potential role in oncogenic transformations resulting in increased kinase activity.

Applications:

WB

Name of antibody:

PTK2 (Phospho-Tyr861)

Immunogen:

Synthetic peptide of human PTK2 (Phospho-Tyr861)

Full name:

protein tyrosine kinase 2 (Phospho-Tyr861)

Synonyms：

FAK; FADK; FAK1; FRNK; PPP1R71; p125FAK; pp125FAK

SwissProt:

Q05397

WB Predicted band size:

125 kDa

WB Positive control:

HT29 cells treated with EGF

WB Recommended dilution:

500-1000