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技术规格
Background:
The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance.
Applications:
ELISA, IHC
Name of antibody:
HAVCR2
Immunogen:
Synthetic peptide of human HAVCR2
Full name:
hepatitis A virus cellular receptor 2
Synonyms:
TIM3; CD366; KIM-3; TIMD3; Tim-3; TIMD-3; HAVcr-2
SwissProt:
Q8TDQ0
ELISA Recommended dilution:
5000-10000
IHC positive control:
Human gastric cancer
IHC Recommend dilution:
10-50