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英文 名称: Anti-TLR4 rabbit polyclonal antibody
别 名: TOLL; CD284; TLR-4; ARMD10
相关类别: 一抗
抗 原: TLR4
储 存: 冷冻(-20℃)
宿 主: Rabbit
反应种属: Human
标 记 物: Unconjugate
克隆类型: rabbit polyclonal
技术规格
Background:
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness.
Applications:
ELISA, IHC
Name of antibody:
TLR4
Immunogen:
Fusion protein of human TLR4
Full name:
toll-like receptor 4
Synonyms:
TOLL; CD284; TLR-4; ARMD10
SwissProt:
O00206
ELISA Recommended dilution:
1000-5000
IHC positive control:
Human colon cancer
IHC Recommend dilution:
50-200