兔抗TCIM多克隆抗体

Background:

This gene encodes a small, monomeric, predominantly unstructured protein that functions as a positive regulator of the Wnt/beta-catenin signaling pathway. This protein interacts with a repressor of beta-catenin mediated transcription at nuclear speckles. It is thought to competitively block interactions of the repressor with beta-catenin, resulting in up-regulation of beta-catenin target genes. The encoded protein may also play a role in the NF-kappaB and ERK1/2 signaling pathways. Expression of this gene may play a role in the proliferation of several types of cancer including thyroid cancer, breast cancer and hematological malignancies. [provided by RefSeq, Nov 2011]

Applications:

ELISA, IHC

Name of antibody:

TCIM

Immunogen:

Fusion protein of human TCIM

Full name:

transcriptional and immune response regulator

Synonyms:

TC1; TC-1; C8orf4

SwissProt:

Q9NR00

IHC positive control:

Human gastric cancer and Human thyroid cancer

IHC Recommend dilution:

40-200