兔抗RAD21多克隆抗体

Background:

The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad21, a gene involved in the repair of DNA double-strand breaks, as well as in chromatid cohesion during mitosis. This protein is a nuclear phospho-protein, which becomes hyperphosphorylated in cell cycle M phase. The highly regulated association of this protein with mitotic chromatin specifically at the centromere region suggests its role in sister chromatid cohesion in mitotic cells.

Applications:

WB

Name of antibody:

RAD21

Immunogen:

Synthesized peptide derived from internal of human RAD21.

Full name:

RAD21 cohesin complex component

Synonyms:

MGS; HR21; MCD1; NXP1; SCC1; CDLS4; hHR21; HRAD21

SwissProt:

O60216

WB Predicted band size:

72 kDa

WB Positive control:

Jurkat cells lysate

WB Recommended dilution:

500-3000