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技术规格
Background:
The protein encoded by this gene is a type B histone acetyltransferase (HAT) that is involved in the rapid acetylation of newly synthesized cytoplasmic histones, which are in turn imported into the nucleus for de novo deposition onto nascent DNA chains. Histone acetylation, particularly of histone H4, plays an important role in replication-dependent chromatin assembly. Specifically, this HAT can acetylate soluble but not nucleosomal histone H4 at lysines 5 and 12, and to a lesser degree, histone H2A at lysine 5.
Applications:
WB
Name of antibody:
HAT1
Immunogen:
Synthesized peptide derived from Internal of human HAT.
Full name:
histone acetyltransferase 1
Synonyms:
KAT1
SwissProt:
O14929
WB Predicted band size:
50 kDa
WB Positive control:
K562 cell lysate
WB Recommended dilution:
500-3000