兔抗RPS6KB1多克隆抗体

Background:

This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates several residues of the S6 ribosomal protein. The kinase activity of this protein leads to an increase in protein synthesis and cell proliferation. Amplification of the region of DNA encoding this gene and overexpression of this kinase are seen in some breast cancer cell lines. Alternate translational start sites have been described and alternate transcriptional splice variants have been observed but have not been thoroughly characterized.

Applications:

ELISA, WB, IHC

Name of antibody:

RPS6KB1

Immunogen:

Fusion protein of human RPS6KB1

Full name:

ribosomal protein S6 kinase, 70kDa, polypeptide 1

Synonyms：

S6K, PS6K, S6K1, STK14A, p70-S6K, p70-alpha, p70(S6K)-alpha

SwissProt:

P23443

ELISA Recommended dilution:

1000-5000

IHC positive control:

Human thyroid cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

59 kDa

WB Positive control:

293T cells

WB Recommended dilution:

200-1000