兔抗SNAP25多克隆抗体

Background:

Synaptic vesicle membrane docking and fusion is mediated by SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) located on the vesicle membrane (v-SNAREs) and the target membrane (t-SNAREs). The assembled v-SNARE/t-SNARE complex consists of a bundle of four helices, one of which is supplied by v-SNARE and the other three by t-SNARE. For t-SNAREs on the plasma membrane, the protein syntaxin supplies one helix and the protein encoded by this gene contributes the other two. Therefore, this gene product is a presynaptic plasma membrane protein involved in the regulation of neurotransmitter release. Two alternative transcript variants encoding different protein isoforms have been described for this gene.

Applications:

ELISA, WB, IHC

Name of antibody:

SNAP25

Immunogen:

Fusion protein of human SNAP25

Full name:

Synaptosomal-associated protein, 25kDa

Synonyms：

RIC4; SEC9; SNAP; RIC-4; SNAP-25; bA416N4.2; dJ1068F16.2

SwissProt:

P60880

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human brain and human thyroid cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

23 kDa

WB Positive control:

Hela cells

WB Recommended dilution:

500-2000