兔抗PAX2多克隆抗体

Background:

PAX2 encodes paired box gene 2, one of many human homologues of the Drosophila melanogaster gene prd. The central feature of this transcription factor gene family is the conserved DNA-binding paired box domain. PAX2 is believed to be a target of transcriptional supression by the tumor suppressor gene WT1. Mutations within PAX2 have been shown to result in optic nerve colobomas and renal hypoplasia. Alternative splicing of this gene results in multiple transcript variants.

Applications:

ELISA, WB

Name of antibody:

PAX2

Immunogen:

Synthetic peptide of human PAX2

Full name:

paired box 2

Synonyms:

FSGS7; PAPRS

SwissProt:

Q02962

ELISA Recommended dilution:

5000-10000

WB Predicted band size:

45 kDa

WB Positive control:

MCF-7 cell lysate

WB Recommended dilution:

500-2000