兔抗SLC10A7多克隆抗体

Background:

The SLC10 family of sodium/bile salt cotransporters contains over 50 members in animal, plant and bacterial species. SLC10A7 (solute carrier family 10 (sodium/bile acid cotransporter family), member 7), also known as P7, is a 358 amino acid multi-pass membrane protein belonging to the sodium:bile acid symporter family. Existing as seven alternatively spliced isoforms, SLC10A7 is expressed at high levels in liver and lung, moderate levels in placenta, kidney, spleen, and thymus, and low levels in heart, prostate, and testis. A few members of the sodium:bile acid symporter family, such as NTCP (also known as SLC10A1) and Asbt (also known as SLC10A2), are involved in maintaining enterohepatic circulation of bile acids by mediating the first step of active bile transport through membrane barriers of liver and intestine. Other family members, including SLC10A6, play an important role in the cellular delivery of specific prohormones in testis, placenta, adrenal gland and other peripheral tissues. Orphan carriers such as SLC10A7 are uncharacterized and their functions unknown.

Applications:

WB

Name of antibody:

SLC10A7

Immunogen:

Synthesized peptide derived from internal of human SLC10A7.

Full name:

solute carrier family 10, member 7

Synonyms:

P7; C4orf13

SwissProt:

Q0GE19

WB Predicted band size:

39 kDa

WB Positive control:

Mouse liver tissue lysate

WB Recommended dilution:

500-3000