兔抗SIN3B多克隆抗体

Background:

Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription (By similarity).

Applications:

ELISA, IHC

Name of antibody:

SIN3B

Immunogen:

Synthetic peptide of human SIN3B

Full name:

SIN3 transcription regulator family member B

SwissProt:

O75182

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human thyroid cancer

IHC Recommend dilution:

25-100