兔抗SGCG多克隆抗体

Background:

This gene encodes gamma-sarcoglycan, one of several sarcolemmal transmembrane glycoproteins that interact with dystrophin. The dystrophin-glycoprotein complex (DGC) spans the sarcolemma and is comprised of dystrophin, syntrophin, alpha- and beta-dystroglycans and sarcoglycans. The DGC provides a structural link between the subsarcolemmal cytoskeleton and the extracellular matrix of muscle cells. Defects in the encoded protein can lead to early onset autosomal recessive muscular dystrophy, in particular limb-girdle muscular dystrophy, type 2C (LGMD2C).

Applications:

ELISA, WB

Name of antibody:

SGCG

Immunogen:

Synthetic peptide of human SGCG

Full name:

sarcoglycan gamma

Synonyms:

A4; MAM; DMDA; SCG3; 35DAG; DAGA4; DMDA1; LGMD2C; SCARMD2; gamma-SG

SwissProt:

Q13326

ELISA Recommended dilution:

5000-10000

WB Predicted band size:

32 kDa

WB Positive control:

Human heart tissue and Mouse heart tissue lysates

WB Recommended dilution:

200-1000