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Background:
This gene encodes a serine/threonine protein kinase that plays an important role in cellular stress response. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. High levels of expression of this gene may contribute to conditions such as hypertension and diabetic nephropathy. Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Applications:
ELISA, IHC
Name of antibody:
SGK1
Immunogen:
Synthetic peptide of human SGK1
Full name:
serum/glucocorticoid regulated kinase 1
Synonyms:
SGK
SwissProt:
O00141
ELISA Recommended dilution:
1000-2000
IHC positive control:
Human liver cancer and Human lung cancer
IHC Recommend dilution:
25-100