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Background:
This gene encodes the catalytic subunit of tRNA-guanine transglycosylase. tRNA-guanine transglycosylase is a heterodimeric enzyme complex that plays a critical role in tRNA modification by synthesizing the 7-deazaguanosine queuosine, which is found in tRNAs that code for asparagine, aspartic acid, histidine and tyrosine. A pseudogene of this gene is located on the long arm of chromosome X.
Applications:
ELISA, IHC
Name of antibody:
QTRT1
Immunogen:
Fusion protein of human QTRT1
Full name:
queuine tRNA-ribosyltransferase catalytic subunit 1
Synonyms:
TGT; TGUT; FP3235
SwissProt:
Q9BXR0
ELISA Recommended dilution:
5000-10000
IHC positive control:
Human thyroid cancer
IHC Recommend dilution:
25-100