兔抗POLE多克隆抗体

Background:

This gene encodes the catalytic subunit of DNA polymerase epsilon. The enzyme is involved in DNA repair and chromosomal DNA replication. Mutations in this gene have been associated with colorectal cancer 12 and facial dysmorphism, immunodeficiency, livedo, and short stature.

Applications:

IHC

Name of antibody:

POLE

Immunogen:

Synthesized peptide derived from internal of human POLE1.

Full name:

polymerase (DNA directed), epsilon, catalytic subunit

Synonyms：

FILS; POLE1; CRCS12

SwissProt:

Q07864

IHC positive control:

Human breast carcinoma tissue

IHC Recommend dilution:

50-100