手机扫码访问本站
微信咨询
技术规格
Background:
Siglec-7, which is highly expressed in monocytes and resident blood cells but not in parenchymatous cells, mediates inhibition of natural killer cell cytotoxicity. Due to alternative splicing events, two isoforms exist for Siglec-12, namely SLG-L (the long isoform) and SLG-S (the shorter isoform). These isoforms are differentially expressed with the longer isoform predominantly found in small intestine, spleen and bone marrow, and the shorter isoform predominantly found in small intestine, spleen and adrenal gland.
Applications:
ELISA, IHC
Name of antibody:
SIGLEC7
Immunogen:
Synthetic peptide of human SIGLEC7
Full name:
sialic acid binding Ig-like lectin 7
Synonyms:
p75; QA79; AIRM1; CD328; CDw328; D-siglec; SIGLEC-7; SIGLECP2; SIGLEC19P; p75/AIRM1
SwissProt:
Q9Y286
ELISA Recommended dilution:
1000-2000
IHC positive control:
Human thyroid cancer and Human brain
IHC Recommend dilution:
25-100