兔抗SF3A3多克隆抗体

Background:

This gene encodes subunit 3 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 3 interacts with subunit 1 through its amino-terminus while the zinc finger domain of subunit 3 plays a role in its binding to the 15S U2 snRNP. This gene has a pseudogene on chromosome 20. Alternative splicing results in multiple transcript variants.

Applications:

ELISA, WB, IHC

Name of antibody:

SF3A3

Immunogen:

Fusion protein of human SF3A3

Full name:

splicing factor 3a subunit 3

Synonyms:

PRP9; PRPF9; SAP61; SF3a60

SwissProt:

Q12874

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human thyroid cancer and Human liver cancer

IHC Recommend dilution:

30-150

WB Predicted band size:

59 kDa

WB Positive control:

Jurkat and Raji cell lysates

WB Recommended dilution:

500-2000